In the field of counterintelligence, a double agent is an employee of a secret intelligence service for one country, whose primary purpose is to spy on a target organization of another country, but who is now spying on their own country's organization for the target organization.[1]
Double agentry may be practised by spies of the target organization who infiltrate the controlling organization or may result from the turning (switching sides) of previously loyal agents of the controlling organization by the target. The threat of execution is the most common method of turning a captured agent (working for an intelligence service) into a double agent (working for a foreign intelligence service) or a double agent into a re-doubled agent. It is unlike a defector, who is not considered an agent as agents are in place to function for an intelligence service and defectors are not, but some consider that defectors in place are agents until they have defected.
The Double Agent
Double agents are often used to transmit disinformation or to identify other agents as part of counter-espionage operations. They are often very trusted by the controlling organization since the target organization will give them true, but useless or even counterproductive, information to pass along.[2]
A re-doubled agent is an agent who gets caught as a double agent and is forced to mislead the foreign intelligence service. F.M. Begoum describes the re-doubled agent as "one whose duplicity in doubling for another service has been detected by his original sponsor and who has been persuaded to reverse his affections again".[2]
A triple agent is a spy who pretends to be a double agent for one side, while they are truthfully a double agent for the other side. Unlike a re-doubled agent, who changes allegiance due to being compromised, a triple agent is usually considered to have been always loyal to their original side. It may also refer to a spy who works for three opposing sides, such that each side thinks the spy works for them alone.
In animal studies, the drug acts like a "double agent"--it protects normal cells from radiation while promoting the death of cancer cells. The red color comes from porphyrin--a compound that helps make up the blood protein hemoglobin.
The drug seems to act like a double agent--it protects normal cells but promotes death of cancer cells. After studying the drug for years, Batinic-Haberle, Mark Dewhirst, DVM, PhD, and colleagues found that once it gets inside normal cells, BMX-001 activates natural anti-oxidant defenses.
The guy who's The Mole on both sides of a conflict. He works for both sides and plays them off against each other. Although often shown as a villain, he can also be a likeable rogue who just happens to have flexible loyalties, or who has problems with both sides and enjoys setting them on each other. He can even be loyal to one side, and willing to engage in the Dirty Business of faking being an agent for the other; The Mole who engages in Becoming the Mask may turn into this.
As the CIA mourns its dead from a devastating suicide bombing in Afghanistan, the questions grow about how professional spies could have been so taken in, failing to spot a double agent and letting a bomber into their midst.
The suicide bomber, who killed some of the CIA's top al Qaeda hunters, lured the agents to the meeting by claiming he had just met with Ayman al-Zawahiri, this country's most wanted terrorist after Osama bin Laden, sources told ABC News.
The death of so many officers, and the failure to identify a double agent, said Bob Baer, is likely to make the CIA gun-shy for quite some time. \"They are going to look at every walk-in, as we call it, as a potential suicide bomber. Everybody is going to be vetted 10, 20 times.\"
As the series progresses it is revealed Adam's boss at MI6 Sir Martin Angelis (Ciarán Hinds) is aware of a double agent for the Russians with the code name Dorian, who was responsible for the fall of Baku. He strongly suspects it's Adam who has committed this act of treason.
Throughout the series it's not clear if it is Adam and as a viewer, it's unclear whether we can trust his actions. Both the CIA and Angelis suspect him of being Dorian as they have access to a tape recording of a phone call between two SVR agents who are talking about a double agent called Dorian.
A metastatic tumor is a clonal representation of the PT if seeded by a single cancer cell and results in polyclonal metastases if seeded by a cluster of CTCs [56]. The conventional model of metastasis proposed that each metastasis is from a single tumor cell. However, salient discovery annulled the notion and showed that metastasis develops from a collection of multiple genetically distinct clones or polyclones [57]. The biological phenomena that triggered the discrete shedding of CTCs as single cells or as clusters from a primary cancerous lesion merely depends on the hypoxic status of tumor cells [58]. CTC clusters are highly enriched for tumor cells undergoing hypoxia, whereas single CTCs are largely normoxic and this intra-tumor hypoxia heightened the rate of CTC cluster shedding and formation of metastases [58]. CTC clusters also develop from oligoclonal tumor cell groupings by excessive production of cell junction component plakoglobin, which is known to arbitrate intercellular adhesion and increase the metastatic potential of tumor cells up to 50-fold [59]. Plakoglobin (or γ-catenin) interacts with several intracellular molecules including signaling proteins and transcription factors, which accounts for its involvement in cellular and oncological signaling [60]. A comparative gene expression analysis of CTCs, lung metastases and localized DTCs revealed that plakoglobin unified the cytokeratin 14 expressing (CK14+) oligoclonal CTC clusters, thereby imparting a low immunogenic profile that contributes to a successful dissemination [59]. In addition, the CK14+ tumor cells are found to be enriched in desmosome and hemidesmosome adhesion complex genes, co-expressed effector molecules of metastasis such as Epiregulin (Ereg), Tenascin C (Tnc), Jagged1 (Jag1) that are collectively involved in niche modelling and are deficient in major histocompatibility (MHC) class II genes, indicating a low immunogenic profile [57]. These CTCs also represent the aggressive CK14+ basal stem cell phenotype capable of colonizing distant organs efficiently [57]. CTC clusters are also found to be enriched in Ki67-positive proliferative cells that are epigenetically modified with activation of the stemness- and proliferation-related transcription factors Oct4, Sox2, Nanog and Sin3a, which also highlights the metastasis-seeding capabilities of CTC clusters than matched single CTCs [61]. Thus, CTC clusters are likely to be causative agents in inducing metastatic seeding of malignancies of the breast.
(DESCRIPTION) A close up, panning down of the double agent blow dry brush against an orange background. Then, a before an after of our model having used the brush. Before, their long auburn hair is limp with flyaways. After, their hair is sleek with body.
(DESCRIPTION) the amike double agent 2-in-1 straightening blow dry brush sits upon an acrylic stand next to two hair ties, all against an orange background. The amika logo dislays above it - shop now.
the smoothest operator in the game. this multi-tasking, 2-in-1 blow dryer straightening brush has 3 settings (blow dryer, thermal brush, and combo) so you can customise your style. the easy-to-use tool styles hair 3x faster*, 2x smoother***, 1.7x shinier**, and reduces frizz by 30%*** for hair that is as smooth as a double agent.
A: there are three main differences between double agent and the hair blow dryer brush. first, hair type! if you have straight, wavy, or loose curls (1-3a), double agent is for you. hair blow dryer brush works for all hair types (1-4c). next, the result. double agent gives your hair a sleek, straight blowout whereas, hair blow dryer brush gives you a bouncy, voluminous blowout. last but not least, usage. double agent has 3 settings. you can use it on damp hair blow dryer brush or blow dryer and straightener combo; or you can use it on dry hair as a styler. hair blow dryer brush is meant to be used on damp hair only as a blow dryer. 2ff7e9595c
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